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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC4
All Species:
19.7
Human Site:
T10
Identified Species:
27.08
UniProt:
Q9NTJ3
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NTJ3
NP_001002800.1
1288
147182
T10
R
K
G
T
Q
P
S
T
A
R
R
R
E
E
G
Chimpanzee
Pan troglodytes
XP_001157958
1288
147223
T10
R
K
G
T
Q
P
S
T
A
R
R
R
E
E
G
Rhesus Macaque
Macaca mulatta
XP_001099428
1287
147121
T10
R
K
G
T
Q
P
S
T
A
R
R
R
E
E
G
Dog
Lupus familis
XP_535848
1288
147094
T10
R
K
G
T
Q
P
S
T
A
R
R
G
R
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CG47
1286
146876
T10
R
K
G
T
K
P
S
T
A
C
H
Q
E
E
G
Rat
Rattus norvegicus
Q9Z1M9
1233
143186
E10
F
L
K
L
I
E
I
E
N
F
K
S
Y
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510551
1069
122201
Chicken
Gallus gallus
NP_989849
1274
145838
R27
S
N
E
E
S
D
N
R
S
L
E
E
I
L
G
Frog
Xenopus laevis
P50532
1290
146971
T10
P
K
K
T
K
T
S
T
A
V
A
R
E
A
T
Zebra Danio
Brachydanio rerio
NP_775360
1289
145687
G10
V
K
T
S
K
T
A
G
R
R
A
A
E
D
S
Tiger Blowfish
Takifugu rubipres
NP_001027927
1326
150958
A11
R
T
T
K
A
S
T
A
A
A
K
P
G
G
K
Fruit Fly
Dros. melanogaster
Q9VJE5
1690
189046
P25
P
V
T
A
D
P
E
P
G
A
T
A
S
K
L
Honey Bee
Apis mellifera
XP_396862
1282
148175
I10
I
P
D
M
D
M
E
I
D
E
E
N
D
L
Y
Nematode Worm
Caenorhab. elegans
Q20060
1549
176553
D18
Q
S
D
E
S
D
S
D
F
D
D
A
P
V
K
Sea Urchin
Strong. purpuratus
XP_797583
1289
146235
L29
I
I
K
E
F
P
I
L
I
E
K
C
Q
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
G10
E
D
E
P
M
G
G
G
E
S
E
P
E
Q
R
Baker's Yeast
Sacchar. cerevisiae
Q12267
1418
162171
T82
F
S
Q
P
T
N
S
T
T
T
S
L
H
V
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.3
94
N.A.
89.5
24
N.A.
67.8
75.3
76.9
67.9
66.7
20.1
45.9
29.9
48.1
Protein Similarity:
100
99.6
98.9
96.5
N.A.
94.8
47.5
N.A.
75
86.3
87.5
83.5
81.2
40.2
63.9
47.5
65.4
P-Site Identity:
100
100
100
80
N.A.
73.3
6.6
N.A.
0
6.6
46.6
20
13.3
6.6
0
6.6
6.6
P-Site Similarity:
100
100
100
80
N.A.
86.6
20
N.A.
0
20
53.3
46.6
26.6
13.3
6.6
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.3
35.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.7
55.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
6
6
0
6
6
42
12
12
18
0
6
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
6
0
6
0
0
0
% C
% Asp:
0
6
12
0
12
12
0
6
6
6
6
0
6
6
0
% D
% Glu:
6
0
12
18
0
6
12
6
6
12
18
6
42
30
6
% E
% Phe:
12
0
0
0
6
0
0
0
6
6
0
0
0
0
0
% F
% Gly:
0
0
30
0
0
6
6
12
6
0
0
6
6
6
36
% G
% His:
0
0
0
0
0
0
0
0
0
0
6
0
6
0
0
% H
% Ile:
12
6
0
0
6
0
12
6
6
0
0
0
6
0
0
% I
% Lys:
0
42
18
6
18
0
0
0
0
0
18
0
0
12
12
% K
% Leu:
0
6
0
6
0
0
0
6
0
6
0
6
0
18
6
% L
% Met:
0
0
0
6
6
6
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
6
0
0
0
6
6
0
6
0
0
6
0
0
0
% N
% Pro:
12
6
0
12
0
42
0
6
0
0
0
12
6
0
12
% P
% Gln:
6
0
6
0
24
0
0
0
0
0
0
6
6
6
0
% Q
% Arg:
36
0
0
0
0
0
0
6
6
30
24
24
6
0
6
% R
% Ser:
6
12
0
6
12
6
48
0
6
6
6
6
6
0
6
% S
% Thr:
0
6
18
36
6
12
6
42
6
6
6
0
0
0
6
% T
% Val:
6
6
0
0
0
0
0
0
0
6
0
0
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _